Products menu

THUNDER® Total CDK2 TR-FRET Cell Signaling Assay Kit

2026-05-15

Price range: USD$409.00 through USD$8,390.00

Sandwich TR-FRET immunoassay designed for the semi-quantitative detection of Human and Mouse Total CDK2 (Cyclin-Dependent Kinase 2; UniProt ID: P24941; Entrez-Gene Id: 1017) in cell lysates. The assay uses the advanced THUNDER® TR-FRET technology and a matched antibody pair specifically optimized and validated for TR-FRET. Full assay validation can be found in the Technical Data Sheet. Detailed assay protocols are described in the Generic User Manual. The assay is compatible with both adherent and suspension cells and can be run under either a one-plate or two-plate protocol. Both methods are homogeneous (no-wash).

All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

SKU: N/A Categories: ,

Additional information

Size

100 points, 500 points, 2500 points, 5000 points, 10000 points

Degradation of Total CDK2 by CPS2 degrader in Jurkat cells
Data show that treatment of Jurkat cells with the selective CDK2 degrader CPS2 degrades total CDK2 in a concentration-dependent manner. In contrast, GAPDH levels are not modulated by CPS2.
Time course of CDK2 degradation by CPS2 degrader
Data show that robust S/B ratio and pharmacology can be obtained after just 1h of incubation.
Z'-factor of CDK2 assay with Jurkat cells
The Z'-factor of 0.74 indicates that the CDK2 assay is robust and suitable for HTS.
CDK2 in NIH/3T3
Data show that selective degradation of CDK2 by CPS2 can be detected in NIH/3T3 cells.