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THUNDER® Total VAV1 TR-FRET Cell Signaling Assay Kit

2026-02-23

Price range: USD$409.00 through USD$8,390.00

Sandwich TR-FRET immunoassay designed for the semi-quantitative detection of Human Total VAV1 (Vav Guanine Nucleotide Exchange factor 1; VAV proto-oncogene 1) in cell lysates. The assay uses the advanced THUNDER® TR-FRET technology and a matched antibody pair specifically optimized and validated for TR-FRET. Full assay validation can be found in the Technical Data Sheet. Detailed assay protocols are described in the Generic User Manual. The assay is compatible with both adherent and suspension cells, and can be run under either a one-plate or two-plate protocol. Both methods are homogeneous (no-wash).

All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

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Degradation of Total VAV1 by VAV1 Degrader-3 in A549 cells
Data show that treatment of Jurkat cells with the molecular glue VAV1 Degrader-3 degrades total VAV1 in a concentration-dependent manner. In contrast, VAV1 levels are not modulated by PROTAC IRAK4 Degrader-7.
Time course of VAV1 degradation by VAV1 Degrader-3
Data show that robust S/B ratio and pharmacology and be obtained after just 1h of incubation.

New clients get a 40% discount and clients get a 25% discount until 27/2/2026

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