Bioauxilium specializes in the design, development and manufacturing of ready-to-use TR-FRET assay kits that simplify laboratory workflow and accelerate drug discovery and life sciences research.
Molecular Devices has evaluated the performance of the THUNDER™ Phospho-ERK1/2 (T202/Y204) TR-FRET Cell Signaling Assay Kit on three TR-FRET compatible multi-mode microplate readers: SpectraMax® iD5, SpectraMax® i3x, and SpectraMax® M5e. The results, summarized in an Application Note, showed robust assay performances on all instruments. Highlights The THUNDER™ Phospho-ERK1/2 (T202/Y204) Assay Kit was tested […]
See moreAn increasing number of pharma and biotech companies, as well as CROs and academic laboratories, are adopting BioAuxilium’s THUNDER® TR-FRET assay platform to quantify key human cytokines and chemokines in cell supernatants. Based on customer feedback, there are 3 key reasons. Reason #1: High performance assays THUNDER® Human Cytokine Assay Kits are designed to measure […]
See moreIn the framework of our ongoing strategic collaboration with BMG LABTECH, we have evaluated the performance of a panel of three THUNDER™ TR-FRET phospho-proteins assays and five human cytokine assays on the flexible and powerful CLARIOstar® Plus multi-mode microplate reader. The results, summarized in the Application Note 361 and in a tutorial showed an excellent assay […]
See moreAs part of our ongoing strategic collaboration with BMG LABTECH, we have recently evaluated the performance of a panel of five THUNDER™ TR-FRET human cytokine assays on the top-of-the-line PHERAstar® FSX multi-mode microplate reader. The results, summarized in the Application Note 365, showed a superb assay performance of our assays on this HTS instrument. Figure 1: THUNDER™ […]
See moreAt the SLAS2022 International Conference and Exhibition in Boston, we announced the expansion of our no-wash THUNDER™ time-resolved Förster resonance energy transfer (TR-FRET) technology portfolio by introducing new cell signaling pathway and biomarker research assay kits, along with a panel of “mix and match” toolbox reagents. The new offerings bring our portfolio to a total of […]
See moreBioAuxilium has published an article in the J Vis Exp (JoVE) Journal (Biochemistry). In this paper, we describe in detail protocols for the simple, sensitive, robust, and cost-effective measurement in a 384-well format of endogenous phosphorylated STAT1/3/4/5/6 proteins, together with total STAT1/3/5/6, in cell lysates using the THUNDER™ TR-FRET platform. In brief: We measured the […]
See moreBioauxilium has initiated strategic collaborations with leading developers of microplate detection instruments to demonstrate the compatibility of its increasingly popular THUNDER™ TR-FRET assay platform with select high-value multimode microplate readers under real assay conditions. Agilent BioTek® has recently evaluated the performance of the THUNDER™ Phospho-AKT pan (S473) TR-FRET Cell Signaling Assay Kit on the Synergy™ […]
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Bioauxilium is proud to announce the publication of an updated Application Note describing for the first time a comparison among three commercial TR-FRET assay platforms for measuring endogenous phosphoproteins in cellular lysates. The results of this head-to-head study demonstrate superior or comparable performance of THUNDER™ Cell Signaling Assays Kits to that of two existing TR‑FRET […]
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